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seqhiker

Genome browser for FASTA, annotation, BAM, and VCF files, with a stacked genome comparison view.

It is heavily inspired by Artemis/ACT. The aim is easier install and use, keeping key functionality of Artemis/ACT, but I have added extra features. It was developed with substantial coding assistance from OpenAI Codex, which helped with implementation, tests, documentation, and benchmarking under human direction and review.

Documentation: https://seqhiker.readthedocs.io/en/

seqhiker screenshot 1 seqhiker screenshot 2
seqhiker screenshot 3 seqhiker screenshot 4

Quick Start

Install

  1. Go to the latest release.
  2. Download the build for your operating system and architecture.
  3. Open the app.

View genomes

  1. Launch seqhiker.
  2. Drag and drop your files into the window.

A sequence file must be included, for example FASTA, GenBank, EMBL, or a GFF3 file with embedded sequence.

Typical files:

  • FASTA
  • GenBank
  • EMBL
  • GFF3
  • BAM (sorted and indexed)
  • VCF

seqhiker will load the files and open the matching genome view.

A standalone GFF3 with an embedded ##FASTA section is treated as a sequence-bearing genome file.

You can also switch to Comparison view in the toolbar and add genomes one-by-one to compare them.

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Genome browser ๐Ÿงฌ๐Ÿ‘€๐Ÿš€

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